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AMP-activated Protein Kinase Activation by 5-Aminoimidazole-4-carbox-amide-1-β-d-ribofuranoside (AICAR) Reduces Lipoteichoic Acid-induced Lung Inflammation

Adenosine monophosphate-activated protein (AMP)-activated kinase (AMPK) is a highly conserved kinase that plays a key role in energy homeostasis. Activation of AMPK was shown to reduce inflammation in response to lipolysaccharide in vitro and in vivo. 5-Aminoimidazole-4-carbox-amide-1-β-d-ribofurano...

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Bibliografische gegevens
Hoofdauteurs: Hoogendijk, Arie J., Pinhanços, Sandra S., van der Poll, Tom, Wieland, Catharina W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591614/
https://ncbi.nlm.nih.gov/pubmed/23322781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413138
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