R-roscovitine Reduces Lung Inflammation Induced by Lipoteichoic Acid and Streptococcus pneumoniae

Bacterial pneumonia remains associated with high morbidity and mortality. The gram-positive pathogen Streptococcus pneumoniae is the most common cause of community-acquired pneumonia. Lipoteichoic acid (LTA) is an important proinflammatory component of the gram-positive bacterial cell wall. R-roscov...

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Detalhes bibliográficos
Main Authors: Hoogendijk, Arie J, Roelofs, Joris J T H, Duitman, JanWillem, van Lieshout, Miriam H P, Blok, Dana C, van der Poll, Tom, Wieland, Catharina W
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475337/
https://ncbi.nlm.nih.gov/pubmed/22692577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00033
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