Complex of Fas-associated Factor 1 (FAF1) with Valosin-containing Protein (VCP)-Npl4-Ufd1 and Polyubiquitinated Proteins Promotes Endoplasmic Reticulum-associated Degradation (ERAD)

Fas-associated factor 1 (FAF1) is a ubiquitin receptor containing multiple ubiquitin-related domains including ubiquitin-associated (UBA), ubiquitin-like (UBL) 1, UBL2, and ubiquitin regulatory X (UBX). We previously showed that N-terminal UBA domain recognizes Lys(48)-ubiquitin linkage to recruit p...

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Detalhes bibliográficos
Main Authors: Lee, Jae-Jin, Park, Joon Kyu, Jeong, Jaeho, Jeon, Hyesung, Yoon, Jong-Bok, Kim, Eunice EunKyeong, Lee, Kong-Joo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591610/
https://ncbi.nlm.nih.gov/pubmed/23293021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.417576
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