Controlling cancer through the autotaxin–lysophosphatidic acid receptor axis

LPA (lysophosphatidic acid, 1-acyl-2-hydroxy-sn-glycero-3-phosphate), is a growth factor-like lipid mediator that regulates many cellular functions, many of which are unique to malignantly transformed cells. The simple chemical structure of LPA and its profound effects in cancer cells has attracted...

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Autori principali: Gotoh, Mari, Fujiwara, Yuko, Yue, Junming, Liu, Jianxiong, Lee, SueChin, Fells, James, Uchiyama, Ayako, Murakami-Murofushi, Kimiko, Kennel, Stephen, Wall, Jonathan, Patil, Renukadevi, Gupte, Renuka, Balazs, Louisa, Miller, Duane D., Tigyi, Gabor J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590848/
https://ncbi.nlm.nih.gov/pubmed/22260662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20110608
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