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Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant.

The degradation of many proteins requires their prior attachment to ubiquitin. Proteolytic substrates are characteristically multiubiquitinated through the formation of ubiquitin-ubiquitin linkages. Lys-48 of ubiquitin can serve as a linkage site in the formation of such chains and is required for t...

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Hlavní autoři: Finley, D, Sadis, S, Monia, B P, Boucher, P, Ecker, D J, Crooke, S T, Chau, V
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC359070/
https://ncbi.nlm.nih.gov/pubmed/8035826
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