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Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant.

The degradation of many proteins requires their prior attachment to ubiquitin. Proteolytic substrates are characteristically multiubiquitinated through the formation of ubiquitin-ubiquitin linkages. Lys-48 of ubiquitin can serve as a linkage site in the formation of such chains and is required for t...

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Udgivet i:Mol Cell Biol
Principais autores: Finley, D, Sadis, S, Monia, B P, Boucher, P, Ecker, D J, Crooke, S T, Chau, V
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359070/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8035826/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.8.5501-5509.1994
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