Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant.
The degradation of many proteins requires their prior attachment to ubiquitin. Proteolytic substrates are characteristically multiubiquitinated through the formation of ubiquitin-ubiquitin linkages. Lys-48 of ubiquitin can serve as a linkage site in the formation of such chains and is required for t...
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| Published in: | Mol Cell Biol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
1994
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359070/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8035826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.8.5501-5509.1994 |
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