Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant.

The degradation of many proteins requires their prior attachment to ubiquitin. Proteolytic substrates are characteristically multiubiquitinated through the formation of ubiquitin-ubiquitin linkages. Lys-48 of ubiquitin can serve as a linkage site in the formation of such chains and is required for t...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Finley, D, Sadis, S, Monia, B P, Boucher, P, Ecker, D J, Crooke, S T, Chau, V
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359070/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8035826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.8.5501-5509.1994
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