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The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover.

The 26S proteasome is an essential proteolytic complex that is responsible for degrading proteins conjugated with ubiquitin. It has been proposed that the recognition of substrates by the 26S proteasome is mediated by a multiubiquitin-chain-binding protein that has previously been characterized in b...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: van Nocker, S, Sadis, S, Rubin, D M, Glickman, M, Fu, H, Coux, O, Wefes, I, Finley, D, Vierstra, R D
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231604/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8887631/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.11.6020
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