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A novel role for the mitochondrial HTRA2/OMI protease in aging
HTRA2/OMI is an ATP-independent serine protease located in the intermembrane space of the mitochondria and is thought to function as a protein quality control protease. Our previous studies showed that loss of the enzymatic activity of HTRA2 due to a Ser276Cys missense mutation in its catalytic doma...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3590264/ https://ncbi.nlm.nih.gov/pubmed/23242108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22920 |
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