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The DEAD-box helicase eIF4A: Paradigm or the odd one out?

DEAD-box helicases catalyze the ATP-dependent unwinding of RNA duplexes. They share a helicase core formed by two RecA-like domains that carries a set of conserved motifs contributing to ATP binding and hydrolysis, RNA binding and duplex unwinding. The translation initiation factor eIF4A is the foun...

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Autori principali: Andreou, Alexandra Z., Klostermeier, Dagmar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590233/
https://ncbi.nlm.nih.gov/pubmed/22995829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.21966
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