A randomized phase II study to evaluate tacrolimus in combination with sirolimus or methotrexate after allogeneic hematopoietic cell transplantation

BACKGROUND: There is evidence suggesting that sirolimus, in combination with tacrolimus, is active in the prevention of graft-versus-host disease. Sirolimus-based immune suppression may suppress alloreactive T cells, while sparing the survival and function of regulatory T cells. DESIGN AND METHODS:...

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Dades bibliogràfiques
Autors principals: Pidala, Joseph, Kim, Jongphil, Jim, Heather, Kharfan-Dabaja, Mohamed A., Nishihori, Taiga, Fernandez, Hugo F., Tomblyn, Marcie, Perez, Lia, Perkins, Janelle, Xu, Mian, Janssen, William E., Veerapathran, Anandaraman, Betts, Brian C., Locke, Frederick L., Ayala, Ernesto, Field, Teresa, Ochoa, Leonel, Alsina, Melissa, Anasetti, Claudio
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2012
Matèries:
Original Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590095/
https://ncbi.nlm.nih.gov/pubmed/22689677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.067140
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