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Hexosamine Biosynthesis Impairs Insulin Action via a Cholesterolgenic Response
Plasma membrane cholesterol accumulation has been implicated in cellular insulin resistance. Given the role of the hexosamine biosynthesis pathway (HBP) as a sensor of nutrient excess, coupled to its involvement in the development of insulin resistance, we delineated whether excess glucose flux thro...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589672/ https://ncbi.nlm.nih.gov/pubmed/23315940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1213 |
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