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Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system
The spliceosome is a single-turnover enzyme that needs to be dismantled after catalysis to both release the mRNA and recycle small nuclear ribonucleoproteins (snRNPs) for subsequent rounds of pre-mRNA splicing. The RNP remodeling events occurring during spliceosome disassembly are poorly understood,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589558/ https://ncbi.nlm.nih.gov/pubmed/23431055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.207779.112 |
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