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Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system

The spliceosome is a single-turnover enzyme that needs to be dismantled after catalysis to both release the mRNA and recycle small nuclear ribonucleoproteins (snRNPs) for subsequent rounds of pre-mRNA splicing. The RNP remodeling events occurring during spliceosome disassembly are poorly understood,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fourmann, Jean-Baptiste, Schmitzová, Jana, Christian, Henning, Urlaub, Henning, Ficner, Ralf, Boon, Kum-Loong, Fabrizio, Patrizia, Lührmann, Reinhard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589558/
https://ncbi.nlm.nih.gov/pubmed/23431055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.207779.112
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