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DNMT1 represses p53 to maintain progenitor cell survival during pancreatic organogenesis

In the developing pancreas, self-renewal of progenitors and patterning of cell fates are coordinated to ensure the correct size and cellular makeup of the organ. How this coordination is achieved, however, is not clear. We report that deletion of DNA methyltransferase 1 (Dnmt1) in pancreatic progeni...

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Bibliografische gegevens
Hoofdauteurs: Georgia, Senta, Kanji, Murtaza, Bhushan, Anil
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589554/
https://ncbi.nlm.nih.gov/pubmed/23431054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.207001.112
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