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DNMT1 represses p53 to maintain progenitor cell survival during pancreatic organogenesis
In the developing pancreas, self-renewal of progenitors and patterning of cell fates are coordinated to ensure the correct size and cellular makeup of the organ. How this coordination is achieved, however, is not clear. We report that deletion of DNA methyltransferase 1 (Dnmt1) in pancreatic progeni...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589554/ https://ncbi.nlm.nih.gov/pubmed/23431054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.207001.112 |
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