Structural Characterization of the Self-Association of the Death Domain of p75(NTR)

The neurotrophin receptor p75(NTR) conveys multiple signals via its intracellular death domain. However, how the death domain is activated and interacts with downstream adaptors remains unclear. Here, we report two crystal structures of the p75(NTR) death domain in the form of a non-covalent asymmet...

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Hlavní autoři: Qu, Qianhui, Chen, Jun, Wang, Yizhi, Gui, Wenjun, Wang, Li, Fan, Zusen, Jiang, Tao
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589453/
https://ncbi.nlm.nih.gov/pubmed/23472109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057839
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