Structural Characterization of the Self-Association of the Death Domain of p75(NTR)

The neurotrophin receptor p75(NTR) conveys multiple signals via its intracellular death domain. However, how the death domain is activated and interacts with downstream adaptors remains unclear. Here, we report two crystal structures of the p75(NTR) death domain in the form of a non-covalent asymmet...

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Main Authors: Qu, Qianhui, Chen, Jun, Wang, Yizhi, Gui, Wenjun, Wang, Li, Fan, Zusen, Jiang, Tao
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589453/
https://ncbi.nlm.nih.gov/pubmed/23472109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057839
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