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The p75NTR extracellular domain: A potential molecule regulating the solubility and removal of amyloid-β

Senile plaque composed of amyloid-beta (Aβ) in the brain is one of the hallmarks of Alzheimer disease (AD). Removal of Aβ from the brain is the most important therapeutic strategy for AD. The solubility of Aβ is critical for its endocytosis, transcytosis and removal from the brain. Our recent study...

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Autori principali: Zhou, Xin-Fu, Wang, Yan-Jiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226041/
https://ncbi.nlm.nih.gov/pubmed/21814043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.3.16896
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