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The p75NTR extracellular domain: A potential molecule regulating the solubility and removal of amyloid-β

Senile plaque composed of amyloid-beta (Aβ) in the brain is one of the hallmarks of Alzheimer disease (AD). Removal of Aβ from the brain is the most important therapeutic strategy for AD. The solubility of Aβ is critical for its endocytosis, transcytosis and removal from the brain. Our recent study...

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Detalhes bibliográficos
Main Authors: Zhou, Xin-Fu, Wang, Yan-Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226041/
https://ncbi.nlm.nih.gov/pubmed/21814043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.3.16896
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