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Structural Characterization of the Self-Association of the Death Domain of p75(NTR)
The neurotrophin receptor p75(NTR) conveys multiple signals via its intracellular death domain. However, how the death domain is activated and interacts with downstream adaptors remains unclear. Here, we report two crystal structures of the p75(NTR) death domain in the form of a non-covalent asymmet...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589453/ https://ncbi.nlm.nih.gov/pubmed/23472109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057839 |
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