GATA and Ets cis-acting sequences mediate megakaryocyte-specific expression.

The human glycoprotein IIB (GPIIB) gene is expressed only in megakaryocytes, and its promoter displays cell type specificity. We show that this specificity involved two cis-acting sequences. The first one, located at -55, contains a GATA binding site. Point mutations that abolish protein binding on...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Lemarchandel, V, Ghysdael, J, Mignotte, V, Rahuel, C, Roméo, P H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358945/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8417360/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.1.668-676.1993
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!