GATA and Ets cis-acting sequences mediate megakaryocyte-specific expression.
The human glycoprotein IIB (GPIIB) gene is expressed only in megakaryocytes, and its promoter displays cell type specificity. We show that this specificity involved two cis-acting sequences. The first one, located at -55, contains a GATA binding site. Point mutations that abolish protein binding on...
保存先:
| 出版年: | Mol Cell Biol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
1993
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358945/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8417360/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.1.668-676.1993 |
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