GATA and Ets cis-acting sequences mediate megakaryocyte-specific expression.

The human glycoprotein IIB (GPIIB) gene is expressed only in megakaryocytes, and its promoter displays cell type specificity. We show that this specificity involved two cis-acting sequences. The first one, located at -55, contains a GATA binding site. Point mutations that abolish protein binding on...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Lemarchandel, V, Ghysdael, J, Mignotte, V, Rahuel, C, Roméo, P H
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1993
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358945/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8417360/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.1.668-676.1993
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