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Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RI alpha of cyclic AMP-dependent protein kinase A.

The ret oncogene frequently has been found activated in papillary thyroid carcinomas. A previous characterization of ret activation revealed recombination of its tyrosine kinase domain and sequences derived from an uncharacterized locus (D10S170). The mechanism leading to this recombination was iden...

詳細記述

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書誌詳細
主要な著者: Bongarzone, I, Monzini, N, Borrello, M G, Carcano, C, Ferraresi, G, Arighi, E, Mondellini, P, Della Porta, G, Pierotti, M A
フォーマット: Artigo
言語:Inglês
出版事項: 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC358915/
https://ncbi.nlm.nih.gov/pubmed/7678053
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