Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RI alpha of cyclic AMP-dependent protein kinase A.

The ret oncogene frequently has been found activated in papillary thyroid carcinomas. A previous characterization of ret activation revealed recombination of its tyrosine kinase domain and sequences derived from an uncharacterized locus (D10S170). The mechanism leading to this recombination was iden...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Bongarzone, I, Monzini, N, Borrello, M G, Carcano, C, Ferraresi, G, Arighi, E, Mondellini, P, Della Porta, G, Pierotti, M A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 1993
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358915/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7678053/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.1.358
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