PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans

Intramuscular accumulation of triacylglycerol, in the form of lipid droplets (LD), has gained widespread attention as a hallmark of metabolic disease and insulin resistance. Paradoxically, LDs also amass in muscles of highly trained endurance athletes who are exquisitely insulin sensitive. Understan...

Full description

Saved in:
Bibliographic Details
Main Authors: Koves, Timothy R., Sparks, Lauren M., Kovalik, J. P., Mosedale, Merrie, Arumugam, Ramamani, DeBalsi, Karen L., Everingham, Karen, Thorne, Leigh, Phielix, Esther, Meex, Ruth C., Kien, C. Lawrence, Hesselink, Matthijs K. C., Schrauwen, Patrick, Muoio, Deborah M.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2013
Subjects:
Patient-Oriented and Epidemiological Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588877/
https://ncbi.nlm.nih.gov/pubmed/23175776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P028910
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items