Long–echo time MR spectroscopy for skeletal muscle acetylcarnitine detection

Animal models suggest that acetylcarnitine production is essential for maintaining metabolic flexibility and insulin sensitivity. Because current methods to detect acetylcarnitine involve biopsy of the tissue of interest, noninvasive alternatives to measure acetylcarnitine concentrations could facil...

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Vydáno v:J Clin Invest
Hlavní autoři: Lindeboom, Lucas, Nabuurs, Christine I., Hoeks, Joris, Brouwers, Bram, Phielix, Esther, Kooi, M. Eline, Hesselink, Matthijs K.C., Wildberger, Joachim E., Stevens, Robert D., Koves, Timothy, Muoio, Deborah M., Schrauwen, Patrick, Schrauwen-Hinderling, Vera B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2014
Témata:
Technical Advance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347229/
https://ncbi.nlm.nih.gov/pubmed/25271624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74830
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