Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage.

The rad2 mutant of Schizosaccharomyces pombe is sensitive to UV irradiation and deficient in the repair of UV damage. In addition, it has a very high degree of chromosome loss and/or nondisjunction. We have cloned the rad2 gene and have shown it to be a member of the Saccharomyces cerevisiae RAD2/S....

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出版年:	Mol Cell Biol
主要な著者:	Murray, J M, Tavassoli, M, al-Harithy, R, Sheldrick, K S, Lehmann, A R, Carr, A M, Watts, F Z
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis 1994
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358860/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8007985/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.7.4878-4888.1994
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Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage.

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