Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage.

The rad2 mutant of Schizosaccharomyces pombe is sensitive to UV irradiation and deficient in the repair of UV damage. In addition, it has a very high degree of chromosome loss and/or nondisjunction. We have cloned the rad2 gene and have shown it to be a member of the Saccharomyces cerevisiae RAD2/S....

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Murray, J M, Tavassoli, M, al-Harithy, R, Sheldrick, K S, Lehmann, A R, Carr, A M, Watts, F Z
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1994
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358860/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8007985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.7.4878
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