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Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage.

The rad2 mutant of Schizosaccharomyces pombe is sensitive to UV irradiation and deficient in the repair of UV damage. In addition, it has a very high degree of chromosome loss and/or nondisjunction. We have cloned the rad2 gene and have shown it to be a member of the Saccharomyces cerevisiae RAD2/S....

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Murray, J M, Tavassoli, M, al-Harithy, R, Sheldrick, K S, Lehmann, A R, Carr, A M, Watts, F Z
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1994
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358860/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8007985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.7.4878-4888.1994
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