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Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage.

The rad2 mutant of Schizosaccharomyces pombe is sensitive to UV irradiation and deficient in the repair of UV damage. In addition, it has a very high degree of chromosome loss and/or nondisjunction. We have cloned the rad2 gene and have shown it to be a member of the Saccharomyces cerevisiae RAD2/S....

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Publicat a:Mol Cell Biol
Autors principals: Murray, J M, Tavassoli, M, al-Harithy, R, Sheldrick, K S, Lehmann, A R, Carr, A M, Watts, F Z
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1994
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358860/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8007985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.7.4878-4888.1994
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