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Siglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions
Siglecs (sialic acid immunoglobulin-like lectins) are members of the immunoglobulin gene family that contain sialoside binding N-terminal domains. They are cell surface proteins found predominantly on cells of the immune system. Among them, Siglec-8 is uniquely expressed by human eosinophils and mas...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587973/ https://ncbi.nlm.nih.gov/pubmed/22749793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2012.06.005 |
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