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Siglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions

Siglecs (sialic acid immunoglobulin-like lectins) are members of the immunoglobulin gene family that contain sialoside binding N-terminal domains. They are cell surface proteins found predominantly on cells of the immune system. Among them, Siglec-8 is uniquely expressed by human eosinophils and mas...

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Detalhes bibliográficos
Main Authors: Kiwamoto, Takumi, Kawasaki, Norihito, Paulson, James C., Bochner, Bruce S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587973/
https://ncbi.nlm.nih.gov/pubmed/22749793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2012.06.005
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