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Amyloid-β(1–42) Protofibrils Formed in Modified Artificial Cerebrospinal Fluid Bind and Activate Microglia

Soluble aggregated forms of amyloid-β protein (Aβ) have garnered significant attention recently for their role in Alzheimer’s disease (AD). Protofibrils are a subset of these soluble species and are considered intermediates in the aggregation pathway to mature Aβ fibrils. Biological studies have dem...

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Main Authors: Paranjape, Geeta S., Terrill, Shana E., Gouwens, Lisa K., Ruck, Benjamin M., Nichols, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587657/
https://ncbi.nlm.nih.gov/pubmed/23242692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-012-9424-6
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