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Isolated Amyloid-β(1–42) Protofibrils, But Not Isolated Fibrils, Are Robust Stimulators of Microglia

[Image: see text] Senile plaques composed of amyloid-β protein (Aβ) are an unshakable feature of the Alzheimer’s disease (AD) brain. Although there is significant debate on the role of the plaques in AD progression, there is little disagreement on their role in stimulating a robust inflammatory resp...

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Detalhes bibliográficos
Main Authors: Paranjape, Geeta S., Gouwens, Lisa K., Osborn, David C., Nichols, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402375/
https://ncbi.nlm.nih.gov/pubmed/22860196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn2001238
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