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Isolated Amyloid-β(1–42) Protofibrils, But Not Isolated Fibrils, Are Robust Stimulators of Microglia

[Image: see text] Senile plaques composed of amyloid-β protein (Aβ) are an unshakable feature of the Alzheimer’s disease (AD) brain. Although there is significant debate on the role of the plaques in AD progression, there is little disagreement on their role in stimulating a robust inflammatory resp...

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Bibliografski detalji
Glavni autori: Paranjape, Geeta S., Gouwens, Lisa K., Osborn, David C., Nichols, Michael R.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2012
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402375/
https://ncbi.nlm.nih.gov/pubmed/22860196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn2001238
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