Immunosurveillance against tetraploidization-induced colon tumorigenesis

Circumstantial evidence suggests that colon carcinogenesis can ensue the transient tetraploidization of (pre-)malignant cells. In line with this notion, the tumor suppressors APC and TP53, both of which are frequently inactivated in colon cancer, inhibit tetraploidization in vitro and in vivo. Here,...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Boilève, Alice, Senovilla, Laura, Vitale, Ilio, Lissa, Delphine, Martins, Isabelle, Métivier, Didier, van den Brink, Stieneke, Clevers, Hans, Galluzzi, Lorenzo, Castedo, Maria, Kroemer, Guido
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587448/
https://ncbi.nlm.nih.gov/pubmed/23324343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23369
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky