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Caspase 2 in mitotic catastrophe: The terminator of aneuploid and tetraploid cells

Mitotic catastrophe is an oncosuppressive mechanism that targets cells experiencing defective mitoses via the activation of specific cell cycle checkpoints, regulated cell death pathways and/or cell senescence. This prevents the accumulation of karyotypic aberrations, which otherwise may drive oncog...

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Detalles Bibliográficos
Publicado en:Mol Cell Oncol
Main Authors: Vitale, Ilio, Manic, Gwenola, Castedo, Maria, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462511/
https://ncbi.nlm.nih.gov/pubmed/28616577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1299274
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