Mitochondrial topoisomerase II activity is essential for kinetoplast DNA minicircle segregation.

Etoposide, a nonintercalating antitumor drug, is a potent inhibitor of topoisomerase II activity. When Trypanosoma equiperdum is treated with etoposide, cleavable complexes are stabilized between topoisomerase II and kinetoplast DNA minicircles, a component of trypanosome mitochondrial DNA (T. A. Sh...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Mol Cell Biol
Autore principale:	Shapiro, T A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8196610/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.6.3660-3667.1994
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!