Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

Mapping of epitopes recognized by functional monoclonal antibodies (mAbs) is essential for understanding the nature of immune responses and designing improved vaccines, therapeutics, and diagnostics. In recent years, identification of B-cell epitopes targeted by neutralizing antibodies has facilitat...

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Autors principals: Malito, Enrico, Faleri, Agnese, Lo Surdo, Paola, Veggi, Daniele, Maruggi, Giulietta, Grassi, Eva, Cartocci, Elena, Bertoldi, Isabella, Genovese, Alessia, Santini, Laura, Romagnoli, Giacomo, Borgogni, Erica, Brier, Sébastien, Lo Passo, Carla, Domina, Maria, Castellino, Flora, Felici, Franco, van der Veen, Stijn, Johnson, Steven, Lea, Susan M., Tang, Christoph M., Pizza, Mariagrazia, Savino, Silvana, Norais, Nathalie, Rappuoli, Rino, Bottomley, Matthew J., Masignani, Vega
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587270/
https://ncbi.nlm.nih.gov/pubmed/23396847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222845110
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