4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp

Neisseria meningitidis serogroup B (MenB) is the leading cause of meningococcal meningitis and sepsis in industrialized countries, with the highest incidence in infants and adolescents. Two recombinant protein vaccines that protect against MenB are now available (i.e. 4CMenB and MenB-fHbp). Both vac...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Veggi, Daniele, Bianchi, Federica, Santini, Laura, Lo Surdo, Paola, Chesterman, Chelsy C., Pansegrau, Werner, Bechi, Nicoletta, Huang, Ying, Masignani, Vega, Pizza, Mariagrazia, Rappuoli, Rino, Bottomley, Matthew J., Cozzi, Roberta, Maione, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556464/
https://ncbi.nlm.nih.gov/pubmed/33007046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008882
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