Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

Mapping of epitopes recognized by functional monoclonal antibodies (mAbs) is essential for understanding the nature of immune responses and designing improved vaccines, therapeutics, and diagnostics. In recent years, identification of B-cell epitopes targeted by neutralizing antibodies has facilitat...

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Hlavní autoři: Malito, Enrico, Faleri, Agnese, Lo Surdo, Paola, Veggi, Daniele, Maruggi, Giulietta, Grassi, Eva, Cartocci, Elena, Bertoldi, Isabella, Genovese, Alessia, Santini, Laura, Romagnoli, Giacomo, Borgogni, Erica, Brier, Sébastien, Lo Passo, Carla, Domina, Maria, Castellino, Flora, Felici, Franco, van der Veen, Stijn, Johnson, Steven, Lea, Susan M., Tang, Christoph M., Pizza, Mariagrazia, Savino, Silvana, Norais, Nathalie, Rappuoli, Rino, Bottomley, Matthew J., Masignani, Vega
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587270/
https://ncbi.nlm.nih.gov/pubmed/23396847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222845110
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