Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells

Protein ubiquitination regulates important innate immune responses. The discovery of viruses encoding deubiquitinating enzymes (DUBs) suggests they remove ubiquitin to evade ubiquitin-dependent antiviral responses; however, this has never been conclusively demonstrated in virus-infected cells. Arter...

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Autores principales: van Kasteren, Puck B., Bailey-Elkin, Ben A., James, Terrence W., Ninaber, Dennis K., Beugeling, Corrine, Khajehpour, Mazdak, Snijder, Eric J., Mark, Brian L., Kikkert, Marjolein
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
Materias:
PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587229/
https://ncbi.nlm.nih.gov/pubmed/23401522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218464110
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