Arterivirus and Nairovirus Ovarian Tumor Domain-Containing Deubiquitinases Target Activated RIG-I To Control Innate Immune Signaling

The innate immune response constitutes the first line of defense against viral infection and is extensively regulated through ubiquitination. The removal of ubiquitin from innate immunity signaling factors by deubiquitinating enzymes (DUBs) therefore provides a potential opportunity for viruses to e...

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Bibliografiska uppgifter
Huvudupphovsmän: van Kasteren, Puck B., Beugeling, Corrine, Ninaber, Dennis K., Frias-Staheli, Natalia, van Boheemen, Sander, García-Sastre, Adolfo, Snijder, Eric J., Kikkert, Marjolein
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2012
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255818/
https://ncbi.nlm.nih.gov/pubmed/22072774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06277-11
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