Arterivirus and Nairovirus Ovarian Tumor Domain-Containing Deubiquitinases Target Activated RIG-I To Control Innate Immune Signaling

The innate immune response constitutes the first line of defense against viral infection and is extensively regulated through ubiquitination. The removal of ubiquitin from innate immunity signaling factors by deubiquitinating enzymes (DUBs) therefore provides a potential opportunity for viruses to e...

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Detalhes bibliográficos
Main Authors: van Kasteren, Puck B., Beugeling, Corrine, Ninaber, Dennis K., Frias-Staheli, Natalia, van Boheemen, Sander, García-Sastre, Adolfo, Snijder, Eric J., Kikkert, Marjolein
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255818/
https://ncbi.nlm.nih.gov/pubmed/22072774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06277-11
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