Arterivirus and Nairovirus Ovarian Tumor Domain-Containing Deubiquitinases Target Activated RIG-I To Control Innate Immune Signaling

The innate immune response constitutes the first line of defense against viral infection and is extensively regulated through ubiquitination. The removal of ubiquitin from innate immunity signaling factors by deubiquitinating enzymes (DUBs) therefore provides a potential opportunity for viruses to e...

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Autori principali: van Kasteren, Puck B., Beugeling, Corrine, Ninaber, Dennis K., Frias-Staheli, Natalia, van Boheemen, Sander, García-Sastre, Adolfo, Snijder, Eric J., Kikkert, Marjolein
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255818/
https://ncbi.nlm.nih.gov/pubmed/22072774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06277-11
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