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Selective capacity of metreleptin administration to reconstitute CD4(+) T-cell number in females with acquired hypoleptinemia
Leptin is an adipocyte-derived hormone that controls food intake and reproductive and immune functions in rodents. In uncontrolled human studies, low leptin levels are associated with impaired immune responses and reduced T-cell counts; however, the effects of leptin replacement on the adaptive immu...
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Autors principals: | , , , , , , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
National Academy of Sciences
2013
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587204/ https://ncbi.nlm.nih.gov/pubmed/23382191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214554110 |
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