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Nanoprobing of the effect of Cu(2+) cations on misfolding, interaction and aggregation of amyloid β peptide
Misfolding and aggregation of the amyloid β-protein (Aβ) are hallmarks of Alzheimer’s disease. Both processes are dependent on the environmental conditions, including the presence of divalent cations, such as Cu(2+). Cu(2+) cations regulate early stages of Aβ aggregation, but the molecular mechanism...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3586772/ https://ncbi.nlm.nih.gov/pubmed/23143330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-012-9416-6 |
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