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Nanoprobing of the effect of Cu(2+) cations on misfolding, interaction and aggregation of amyloid β peptide

Misfolding and aggregation of the amyloid β-protein (Aβ) are hallmarks of Alzheimer’s disease. Both processes are dependent on the environmental conditions, including the presence of divalent cations, such as Cu(2+). Cu(2+) cations regulate early stages of Aβ aggregation, but the molecular mechanism...

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Detalhes bibliográficos
Main Authors: Lv, Zhengjian, Condron, Margaret M., Teplow, David B., Lyubchenko, Yuri L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586772/
https://ncbi.nlm.nih.gov/pubmed/23143330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-012-9416-6
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