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Molecular Mechanism of Misfolding and Aggregation of Aβ (13–23)
The misfolding and self-assembly of the amyloid-beta (Aβ) peptide into aggregates is a molecular signature of the development of Alzheimer’s disease but molecular mechanisms of the peptide aggregation remain unknown. Here, we combined Atomic Force Microscopy (AFM) and Molecular Dynamics (MD) simulat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3695694/ https://ncbi.nlm.nih.gov/pubmed/23642026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp402938p |
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