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Amyloid misfolding, aggregation, and the early onset of protein deposition diseases: insights from AFM experiments and computational analyses

The development of Alzheimer’s disease is believed to be caused by the assembly of amyloid β proteins into aggregates and the formation of extracellular senile plaques. Similar models suggest that structural misfolding and aggregation of proteins are associated with the early onset of diseases such...

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Detalhes bibliográficos
Publicado no:AIMS Mol Sci
Autor principal: Lyubchenko, Yuri L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098429/
https://ncbi.nlm.nih.gov/pubmed/27830177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3934/molsci.2015.3.190
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