Gadolinium MRI Contrast Agents Based on Triazine Dendrimers: Relaxivity and In Vivo Pharmacokinetics

Four gadolinium (Gd)-based macromolecular contrast agents, G3-(Gd-DOTA)(24), G5-(Gd-DOTA)(96), G3-(Gd-DTPA)(24), and G5-(Gd-DTPA)(96), were prepared that varied in the size of dendrimer (generation three and five), the type of chelate group (DTPA or DOTA), and the theoretical number of metallated ch...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lim, Jongdoo, Turkbey, Baris, Bernardo, Marcelino, Bryant, L. Henry, Garzoni, Matteo, Pavan, Giovanni M., Nakajima, Takahito, Choyke, Peter L., Simanek, Eric E., Kobayashi, Hisataka
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586605/
https://ncbi.nlm.nih.gov/pubmed/23035964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc300461r
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